Letter: Azathioprine in psoriasis.
نویسندگان
چکیده
منابع مشابه
Fast atrial fibrillation induced by treatment of psoriasis with azathioprine.
3 Rivlin RS, Young EA, eds. Symposium on evidence relating selected vitamins and minerals to health and disease in the elderly population in the United States.competence of the elderly. Effect of short term nutritional supplementation on cell-mediated immunity and lymphocyte subsets. Fast atrial fibrillation induced by treatment of psoriasis with azathioprine We describe a patient with psoriasi...
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Introduction: Psoriasis is chronic disease where treatments are often needed throughout life. Since 1806, when Thomas girdlestone used potassium arsenate for Psoriasis to present era, we are still in search of drug which can cure this disease. Azathioprine is a relatively safe drug which has not been tested vigourously for chronic plaque type Psoriasis. Aims and objectives: To evaluate and comp...
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Azathioprine is a synthetic purine analog derived from 6-mercaptopurine. It is a purine antagonist and its active metabolites act by disrupting the function of endogenous purines. It has a cytotoxic and immunosuppressive mechanism of action. It is used in dermatology for treatment of immunobullous diseases, generalized eczematous disorders and photodermatoses. There is an enzyme in the metaboli...
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Azathioprine has been used as an immunosuppressant for over 20 years in cancer chemotherapy, organ transplantation and diseases with confirmed or suspected immune mechanisms. A hypersensitivity reaction manifesting as fever, rash, myalgia and a neutrophil leucocytosis occurring about 2 weeks after exposure is well documented and has been confirmed by challenge testing. Hypotensive reactions are...
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Fifteen years ago, classical immunosuppressive therapy was inconceivable without corticosteroids and azathioprine. A large number of transplantees administering these drugs had successful immunosuppression and good function of the graft over longer period of time. Nevertheless, side-effects of corticosteroids to cardiovascular system (hypertension, congestive heart failure, thrombophlebitis), t...
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ژورنال
عنوان ژورنال: BMJ
سال: 1974
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5916.443